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A-Level Biology A (H420) Specification

The OCR A-Level Biology A specification (H420): 3 papers, 6 modules, 12 practical activity groups (PAGs) and the Practical Endorsement.

Source: OCR, v4.1 (first teaching 2015) · Reviewed by Jonathan Ellis · Last reviewed 2026-08-05

specification overview

OCR A-Level Biology A (H420) is a two-year linear qualification structured around six modules, from foundations in biology through to genetics, evolution and ecosystems. Students sit three written papers at the end of year 13, plus a separate Practical Endorsement (Pass/Fail) covering 12 practical activity groups (PAGs). All papers are synoptic.

specification overview

subject content

  1. 1. Development of practical skills in biology

    All papers
    • Practical skills assessed in written examinations
    • Practical skills assessed in the Practical Endorsement
  2. 2. Foundations in biology

    Components 01 and 02
    • Cell structure
    • Biological molecules; nucleotides and nucleic acids
    • Enzymes
    • Biological membranes
    • Cell division, cell diversity and cellular organisation
  3. 3. Exchange and transport

    Component 01
    • Exchange surfaces
    • Transport in animals
    • Transport in plants
  4. 4. Biodiversity, evolution and disease

    Component 02
    • Communicable diseases, disease prevention and the immune system
    • Biodiversity
    • Classification and evolution
  5. 5. Communication, homeostasis and energy

    Component 01
    • Communication and homeostasis
    • Excretion as an example of homeostatic control
    • Neuronal and hormonal communication
    • Plant and animal responses
    • Photosynthesis and respiration
  6. 6. Genetics, evolution and ecosystems

    Component 02
    • Cellular control and patterns of inheritance
    • Manipulating genomes
    • Cloning and biotechnology
    • Ecosystems, populations and sustainability
subject content

assessment structure

PaperComponent 01 (Biological Processes)
What's assessedModules 1, 2, 3 and 5
Length2h 15m
Marks100
Weight37%
Question typesStructured questions and extended-response questions, including synoptic content
PaperComponent 02 (Biological Diversity)
What's assessedModules 1, 2, 4 and 6
Length2h 15m
Marks100
Weight37%
Question typesStructured questions and extended-response questions, including synoptic content
PaperComponent 03 (Unified Biology)
What's assessedAll six modules
Length1h 30m
Marks70
Weight26%
Question typesSynoptic questions drawing content from across the whole specification

All three components include synoptic assessment. Component 04 is the Practical Endorsement, a non-exam assessment reported separately (Pass/Fail) alongside the A-Level grade.

assessment structure

assessment objectives

AOAO1
What it meansDemonstrate knowledge and understanding of scientific ideas, processes, techniques and procedures.
Overall31-34%
AOAO2
What it meansApply knowledge and understanding of scientific ideas, processes, techniques and procedures, in theoretical and practical contexts and when handling data.
Overall40-43%
AOAO3
What it meansAnalyse, interpret and evaluate scientific information, ideas and evidence to make judgements, reach conclusions and refine practical design and procedures.
Overall25-28%
assessment objectives

required practicals

PracticalPAG1 Microscopy
What it involvesUse of light microscopy, staining, drawing and estimating scale.
PracticalPAG2 Dissection
What it involvesDissection of animal or plant material to observe structure.
PracticalPAG3 Sampling techniques
What it involvesSampling of biodiversity in a habitat using quadrats, transects and other techniques.
PracticalPAG4 Rates of enzyme-controlled reactions
What it involvesInvestigate factors affecting the rate of an enzyme-controlled reaction.
PracticalPAG5 Colorimeter or potometer
What it involvesUse of a colorimeter or potometer to measure a physiological rate.
PracticalPAG6 Chromatography or electrophoresis
What it involvesSeparation of biological molecules using chromatography or electrophoresis.
PracticalPAG7 Microbiological techniques
What it involvesAseptic techniques to culture and investigate microorganisms.
PracticalPAG8 Transport in and out of cells
What it involvesInvestigate diffusion, osmosis and active transport, including factors affecting membrane permeability.
PracticalPAG9 Qualitative testing
What it involvesQualitative reagent tests for carbohydrates, proteins and lipids.
PracticalPAG10 Investigation using data-logger or computer modelling
What it involvesUse of ICT to record and process experimental data.
PracticalPAG11 Investigation into the measurement of plant or animal responses
What it involvesSafe and ethical use of organisms to measure plant or animal responses and physiological functions.
PracticalPAG12 Research skills
What it involvesApply investigative approaches, use online and offline research skills, and correctly cite sources of information.
required practicals

key tips for success

  • Learn the module → component mapping

    Component 01 covers Modules 1, 2, 3 and 5. Component 02 covers Modules 1, 2, 4 and 6. Component 03 (Unified Biology) covers everything. Knowing which module lands in which paper helps focused revision.

  • Take Component 03 seriously

    The Unified Biology paper is 26% of the A Level and pulls synoptic content across all six modules. Practise linking topics from Component 01 and 02 material rather than treating them as separate blocks.

  • Master the 12 PAGs

    The Practical Activity Groups feed into both written-paper questions (all three papers include practical-context questions) and the Practical Endorsement (Pass/Fail). Learn method, apparatus, expected results for each.

  • Build maths fluency

    AO2 is 40-43% of the qualification and includes handling numerical data. Practise Simpson's Index, chi-squared, Hardy-Weinberg, standard deviation, colorimetry calculations and Rf values so they're automatic.

  • Track your Practical Endorsement progress

    Your teacher assesses your competence across the 12 PAGs through the year. Some university science courses require a Pass, so check in regularly to make sure you're on track.

  • Practise extended-response questions

    Components 01 and 02 both include extended-response questions worth 6+ marks. Structure your answer with clear scientific vocabulary, worked reasoning and a linked conclusion.

key tips for success

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