8.12 - Human Drug Studies
Adoption studies in addictive behaviour
Adoption studies are a research method used to explore the relative influences of genetics (nature) and environment (nurture) on behaviours such as addiction. These studies help disentangle these factors by examining individuals who have been separated from their biological families early in life.
How adoption studies work
Adoption studies typically focus on children who were adopted away from their biological parents and raised in different families. This setup allows researchers to compare the impact of genetic inheritance against environmental upbringing.
Process of adoption studies:
- Identifying participants - Researchers select children adopted from biological parents with a history of substance abuse (such as alcohol or drug addiction) and place them with adoptive families without such issues.
- Assessment process - Later in life, these individuals are evaluated for signs of addictive behaviour. Their outcomes are compared to a control group – people whose biological parents did not have substance abuse problems.
- Purpose - This comparison helps determine if addictive tendencies are more likely due to genes passed from biological parents or the environment provided by adoptive families.
By controlling for family learning effects, adoption studies provide evidence on whether addiction has a hereditary component.
Example research: Cloninger (1987) on alcoholism
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Aims - Cloninger's study (1987) aimed to integrate existing research on the genetic links to alcoholism.
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Method - Researchers constructed family trees of large families with a history of alcoholism to trace patterns of inheritance. They then used adoption data to control for environmental learning within families, comparing adopted individuals from alcoholic biological parents to those from non-alcoholic backgrounds.
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Results - The study found evidence of a genetic component, with adopted individuals from alcoholic biological parents showing higher rates of alcoholism compared to controls.
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Conclusions - This supports the idea that alcoholism can be passed down genetically, though environmental factors also play a role.
Surveys in studying drug use and addiction
Surveys are a research method that collects self-report data from participants about their experiences, habits, and opinions, often through questionnaires or interviews. This approach is valuable for gathering information on drug use and addiction.
Key features of surveys
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Surveys can be structured in different ways to suit the research goals, making them flexible for studying complex behaviours like addiction.
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Types of data - They produce quantitative data or qualitative data, depending on the type of questions asked (open or closed).
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Longitudinal design - Some surveys follow the same participants over time to track changes, such as shifts in drug habits or recovery progress.
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Focus areas - Questions might explore causes of addiction, attitudes towards treatments, rates of relapse or recovery success.
Surveys are particularly useful for assessing the scale of drug issues in a population, such as prevalence rates of substance abuse. This helps governments and organisations allocate resources, like funding for treatment programmes.
Benefits of genetic research in addiction
Understanding the genetic basis of addiction has practical applications. The effectiveness of addiction medications varies from person to person due to differences in genetic make-up.
Applications in treatment
- Personalised medicine - Genetic differences affect how people respond to addiction medications, making certain treatments more or less effective.
- Future developments - Genetic tests could identify a patient's specific genetic profile, allowing doctors to prescribe the most suitable medication for that individual.
Ethical considerations in human drug research
When studying drugs and addiction with human participants, researchers must follow guidelines from the British Psychological Society (BPS).
Key ethical guidelines and challenges due to the vulnerable nature of participants
- Informed consent - If someone is under the influence of drugs, they may lack the capacity to give true informed consent, as their judgement could be impaired.
- Privacy and confidentiality - Maintaining privacy and confidentiality becomes complex if participants reveal illegal activities, like drug use, creating a moral dilemma for the researcher, who must balance confidentiality with societal duties, such as reporting crimes.
- Protection from harm - Studies must avoid causing distress. Questioning about addiction origins might uncover repressed memories, leading to emotional pain or even relapse if old triggers re-emerge.
Balancing risks and benefits
Researchers must weigh potential harms against benefits. Discussing drug use can sometimes be cathartic, which might aid recovery. All this needs to be weighed up in the mind of the researcher.